Cayman Chemical | (±)9-HODE | Description (CAS 98524-19-7)

38400 (±)9-HODE

(CAS 98524-19-7)

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(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of rabbit reticulocytes.^1,2 Oxidized LDL contains significant amounts of esterified 9- and 13-HpODEs and HODEs.^3,4

1 Kühn, H., Belkner, J., Wiesner, R. Subcellular distribution of lipoxygenase products in rabbit reticulocyte membranes. Eur J Biochem 191 221-227 (1990).

2 Kühn, H., Belkner, J., Wiesner, R. Metabolism of polyenoic fatty acids by rabbit reticulocytes. Intracellular action of the erythroid lipoxygenase on membrane lipids. Biomed Biochim Acta 49 S25-S30 (1990).

3 Folcik, V.A., Cathcart, M.K. Predominance of esterified hydroperoxy-linoleic acid in human monocyte-oxidized LDL. J Lipid Res 35 1570-1582 (1994).

4 Ku, G., Thomas, C.E., Akeson, A.L., et al. Induction of interleukin 1β expression from human peripheral blood monocyte-derived macrophages by 9-hydroxyoctadecadienoic acid. J Biol Chem 267 14183-14188 (1992).

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Pricing updated 2010-03-19.
Prices are subject to change without notice.

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