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(±)9-HODE

Cayman Chemical Item Number 38400

(CAS 98524-19-7)

(±)9-HODE (CAS 98524-19-7)

See more	Oxylipins (226) Oxidative Injury (258)

Description

(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of rabbit reticulocytes.^1,2 Oxidized LDL contains significant amounts of esterified 9- and 13-HpODEs and HODEs.^3,4

1 Kühn, H., Belkner, J., and Wiesner, R. Subcellular distribution of lipoxygenase products in rabbit reticulocyte membranes. Eur J Biochem 191 221-227 (1990).

2 Kühn, H., Belkner, J., and Wiesner, R. Metabolism of polyenoic fatty acids by rabbit reticulocytes. Intracellular action of the erythroid lipoxygenase on membrane lipids. Biomed Biochim Acta 49 S25-S30 (1990).

3 Folcik, V.A., and Cathcart, M.K. Predominance of esterified hydroperoxy-linoleic acid in human monocyte-oxidized LDL. J Lipid Res 35 1570-1582 (1994).

4 Ku, G., Thomas, C.E., Akeson, A.L., et al. Induction of interleukin 1β expression from human peripheral blood monocyte-derived macrophages by 9-hydroxyoctadecadienoic acid. J Biol Chem 267 14183-14188 (1992).

Formal Name	(±)-9-hydroxy-10E,12Z-octadecadienoic acid
CAS Number	98524-19-7
Molecular Formula	C₁₈H₃₂O₃
Formula Weight	296.5
Formulation	A solution in ethanol
Purity	≥98%
λ_max	234 nm
ε	23
Stability	1 year
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCC/C=C\C=C/C(O)CCCCCCCC(=O)O

Background Reading

Kühn, H., Belkner, J., and Wiesner, R. Subcellular distribution of lipoxygenase products in rabbit reticulocyte membranes. Eur J Biochem 191 221-227 (1990).

Kühn, H., Belkner, J., and Wiesner, R. Metabolism of polyenoic fatty acids by rabbit reticulocytes. Intracellular action of the erythroid lipoxygenase on membrane lipids. Biomed Biochim Acta 49 S25-S30 (1990).

Ku, G., Thomas, C.E., Akeson, A.L., et al. Induction of interleukin 1β expression from human peripheral blood monocyte-derived macrophages by 9-hydroxyoctadecadienoic acid. J Biol Chem 267 14183-14188 (1992).

Folcik, V.A., and Cathcart, M.K. Predominance of esterified hydroperoxy-linoleic acid in human monocyte-oxidized LDL. J Lipid Res 35 1570-1582 (1994).

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(±)9-HODE is available in the following screening library:

Bio-active Lipid II Screening Library (96-Well)

Size	Price	Quantity	Subtotal
100 µg	$69.00		$0.00
500 µg	$311.00		$0.00
1 mg	$552.00		$0.00
5 mg	$2,415.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

(±)9-HpODE Exclusive

9(R)-HODE

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