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9(S)-HODE

Cayman Chemical Item Number 38410

(CAS 73543-67-6)

9(S)-HODE (CAS 73543-67-6)

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Description

9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals.1,2 It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL particles.3

1 Gardner, H.W. Soybean lipoxygenase-1 enzymically forms both (9S)- and (13S)-hydroperoxides from linoleic acid by a pH-dependent mechanism. Biochim Biophys Acta 1001 274-281 (1989).

2 Kühn, H., Belkner, J., and Wiesner, R. Subcellular distribution of lipoxygenase products in rabbit reticulocyte membranes. Eur J Biochem 191 221-227 (1990).

3 Ku, G., Thomas, C.E., Akeson, A.L., et al. Induction of interleukin 1β expression from human peripheral blood monocyte-derived macrophages by 9-hydroxyoctadecadienoic acid. J Biol Chem 267 14183-14188 (1992).

Formal Name 9S-​hydroxy-​10E,​12Z-​octadecadienoic acid
CAS Number 73543-67-6
Molecular Formula C18H32O3
Formula Weight 296.5
Formulation A solution in ethanol
Purity ≥98%
λmax 234 nm
ε 23
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C=C/[C@@H]​(O)​CCCCCCCC(=O)​O

Background Reading

Gardner, H.W. Soybean lipoxygenase-1 enzymically forms both (9S)- and (13S)-hydroperoxides from linoleic acid by a pH-dependent mechanism. Biochim Biophys Acta 1001 274-281 (1989).

Kühn, H., Belkner, J., and Wiesner, R. Subcellular distribution of lipoxygenase products in rabbit reticulocyte membranes. Eur J Biochem 191 221-227 (1990).

Ku, G., Thomas, C.E., Akeson, A.L., et al. Induction of interleukin 1β expression from human peripheral blood monocyte-derived macrophages by 9-hydroxyoctadecadienoic acid. J Biol Chem 267 14183-14188 (1992).
Size Price Quantity Subtotal
100 µg $90.00 $0.00
500 µg $405.00 $0.00
1 mg $720.00 $0.00
5 mg $3,150.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Linoleic Acid
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