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390011 ω-3 Arachidonic Acid-d8
ω-3 Arachidonic Acid-d8 Workbook Links
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Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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ω-3 Arachidonic acid-d8 contains eight deuterium atoms at the 8, 9, 11, 12, 14, 15, 17, and 18 positions. It is intended for use as an internal standard for the quantification of ω-3 arachidonic acid by GC- or LC-mass spectrometry. ω-3 Arachidonic acid is a rare polyunsaturated fatty acid found in trace amounts in dietary sources. ω-3 fatty acids are now known to be essential for infant growth and development and to protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders.1 In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki value of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.2
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1
Neufeld, E.J., Sprecher, H., Evans, R.W., et al. Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase. J Lipid Res 25 288-293 (1984).
2
Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. Am J Clin Nutr 54 438-463 (1991).
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Purchase 390011 ω-3 Arachidonic Acid-d8
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-16.
Prices are subject to change without notice.
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