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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

ω-3 Arachidonic Acid-d8

Cayman Chemical Item Number 390011

ω-3 Arachidonic Acid-d8

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Description

ω-3 Arachidonic acid-d8 contains eight deuterium atoms at the 8, 9, 11, 12, 14, 15, 17, and 18 positions. It is intended for use as an internal standard for the quantification of ω-3 arachidonic acid by GC- or LC-mass spectrometry. ω-3 Arachidonic acid is a rare polyunsaturated fatty acid found in trace amounts in dietary sources. ω-3 fatty acids are now known to be essential for infant growth and development and to protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders.1 In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki value of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.2

1 Neufeld, E.J., Sprecher, H., Evans, R.W., et al. Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase. J Lipid Res 25 288-293 (1984).

2 Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. Am J Clin Nutr 54 438-463 (1991).

Formal Name 8Z,​11Z,​14Z,​17Z-​eicosatetraenoic-​8,​9,​11,​12,​14,​15,​17,​18-​d8 acid
Molecular Formula C20H24D8O2
Formula Weight 312.5
Formulation A solution in methyl acetate
Purity ≥99% deuterated product
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CC/C=C\C/C=C\C/C=C\C/C=C\CCCCCCC(=O)​O

Background Reading

Neufeld, E.J., Sprecher, H., Evans, R.W., et al. Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase. J Lipid Res 25 288-293 (1984).

Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. Am J Clin Nutr 54 438-463 (1991).
Size Price Quantity Subtotal
500 µg $64.00 $0.00
1 mg $122.00 $0.00
5 mg $512.00 $0.00
10 mg $896.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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Arachidonic Acid-d8
ω-3 Arachidonic Acid
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ω-3 Arachidonic Acid methyl ester
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