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13(S)-HOTrE

Cayman Chemical Item Number 39620

(CAS 87984-82-5)

13(S)-HOTrE (CAS 87984-82-5)

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Description

13(S)-HOTrE is the 15-lipoxygenase (15-LO) product of linolenic acid. It has been detected in cell membranes and as the cholesteryl ester associated with the lesions of atherosclerosis, and in the biomembranes of soybeans exposed to 15-LO.1,2

1 Belkner, J., Wiesner, R., Kühn, H., et al. The oxygenation of cholesterol esters by the reticulocyte lipoxygenase. FEBS Lett 279 110-114 (1991).

2 Maccarrone, M., van Aarle, P.G.M., Veldink, G.A., et al. In vitro oxygenation of soybean biomembranes by lipoxygenase-2. Biochim Biophys Acta 1190 164-169 (1994).

Formal Name 13S-​hydroxy-​9Z,​11E,​15Z-​octadecatrienoic acid
CAS Number 87984-82-5
Molecular Formula C18H30O3
Formula Weight 294.4
Formulation A solution in ethanol
Purity ≥98%
λmax 234 nm
ε 23
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CC/C=C\C[C@@H]​(O)​/C=C/C=C\CCCCCCCC(O)​=O

Background Reading

Belkner, J., Wiesner, R., Kühn, H., et al. The oxygenation of cholesterol esters by the reticulocyte lipoxygenase. FEBS Lett 279 110-114 (1991).

Maccarrone, M., van Aarle, P.G.M., Veldink, G.A., et al. In vitro oxygenation of soybean biomembranes by lipoxygenase-2. Biochim Biophys Acta 1190 164-169 (1994).

13(S)-HOTrE is available in the following screening library:

Size Price Quantity Subtotal
100 µg $36.00 $0.00
500 µg $162.00 $0.00
1 mg $288.00 $0.00
5 mg $1,260.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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