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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

5(S)-HpEPE

Cayman Chemical Item Number 42210

5(S)-HpEPE

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Description

5(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-LO on EPA.1 It is metabolized to LTA5, a key intermediate in the formation of the 5-series leukotrienes. Alternatively, 5(S)-HpEPE is reduced to 5(S)-HEPE by peroxidases.

1 Kulkarni, P.S., Kaufman, P.L., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid. J Ocul Pharmacol 3 349-356 (1987).

Formal Name 5S-​hydroperoxy-​6E,​8Z,​11Z,​14Z,​17Z-​eicosapentaenoic acid
Molecular Formula C20H30O4
Formula Weight 334.5
Formulation A solution in ethanol
Purity ≥98%
λmax 236 nm
ε 23
Stability 6 months
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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CC/C=C\C/C=C\C/C=C\C/C=C\C=C/C(OO)​CCCC(=O)​O

Background Reading

Kulkarni, P.S., Kaufman, P.L., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid. J Ocul Pharmacol 3 349-356 (1987).

5(S)-HpEPE is available in the following screening library:

Size Price Quantity Subtotal
25 µg $86.00 $0.00
50 µg $163.00 $0.00
100 µg $310.00 $0.00
250 µg $688.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

12(S)-HpEPE
15(S)-HpEPE
(±)5-HEPE

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