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13(S)-HpOTrE(γ) Exclusive

Cayman Chemical Item Number 45210

(CAS 121107-97-9)

13(S)-HpOTrE(γ) (CAS 121107-97-9)

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Description

13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid.1 Further action of soybean LO-1 converts 13(S)-HpOTrE(γ) to all four isomers of 6,13-DiHOTrE.2 At concentrations greater than 100 µM, 13(S)-HpOTrE(γ) inhibits the activity of soybean LO-1.3

1 Funk, M.O., Isaac, R., and Porter, N.A. Preparation and purification of lipid hydroperoxides from arachidonic and γ-linolenic acids. Lipids 11 113-116 (1976).

2 Kim, M.R., and Sok, D. Formation of 6,13-dihydroxyoctadecatrienoic acid isomers from γ-linolenic acid. Biochem Biophys Res Commun 159 1154-1160 (1989).

3 Kim, M.R., and Sok, D. Irreversible inhibition of soybean lipoxygenase-1 by hydroperoxy acids as substrates. Arch Biochem Biophys 288 270-275 (1991).

Formal Name 13S-​hydroperoxy-​6Z,​9Z,​11E-​octadecatrienoic acid
CAS Number 121107-97-9
Molecular Formula C18H30O4
Formula Weight 310.4
Formulation A solution in ethanol
Purity ≥98%
λmax 236 nm
ε 23
Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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CCCCC[C@H]​(OO)​/C=C/C=C\C/C=C\CCCCC(O)​=O

Background Reading

Kim, M.R., and Sok, D. Irreversible inhibition of soybean lipoxygenase-1 by hydroperoxy acids as substrates. Arch Biochem Biophys 288 270-275 (1991).

Kim, M.R., and Sok, D. Formation of 6,13-dihydroxyoctadecatrienoic acid isomers from γ-linolenic acid. Biochem Biophys Res Commun 159 1154-1160 (1989).

Funk, M.O., Isaac, R., and Porter, N.A. Preparation and purification of lipid hydroperoxides from arachidonic and γ-linolenic acids. Lipids 11 113-116 (1976).

13(S)-HpOTrE(γ) is available in the following screening library:

Size Price Quantity Subtotal
100 µg $42.00 $0.00
500 µg $189.00 $0.00
1 mg $336.00 $0.00
5 mg $1,470.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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13(S)-HpOTrE Exclusive

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