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Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.
Leptin (human) EIA KitCayman Chemical Item Number 500010 Leptin (human) ELISA Kit 
Leptin (human) EIA Kit
Leptin (human) EIA Kit Analysis ToolsCayman offers a variety of analysis tools to assist you.
Description
Limit of detection:
0.5 ng/ml
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Leptin, the product of the ob (obese) gene, is produced mainly in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism, and body weight regulation. The primary effect of leptin appears to be mediated by leptin receptors expressed mainly in the hypothalamus. In humans, leptin levels correlate with body mass index (BMI) and percentage body fat, and are elevated even in obese individuals. Leptin has a dual action; it decreases the appetite and increases energy consumption. Leptin is secreted in circadian fashion with nocturnal rise in both lean and obese patients. Mutations of the ob gene resulting in leptin deficiency are the cause of obesity in the ob/ob mice suggesting that endogeneous leptin can normalize their body weight. In contrast, human obese subjects may have high level of leptin, indicating a mechanism of leptin resistance. This Enzyme Immunometric Assay (EIA) is based on a double-
Background ReadingLichnovská, R., Gwozdziewiczová, S., and Hrebícek, J. Gender differences in factors influencing insulin resistance in elderly hyperlipemic non- Adam, J.A., Menheere, P.P.C.A., van Dielen, F.M.H., et al. Decreased plasma orexin- Haluzík, M., indelka, G., Widimský, J., et al. Serum leptin levels in patients with primary hyperaldosteronism before and after treatment: Relationships to insulin sensitivity.. J Hum Hypertens 16 41-45 (2002). |
This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase.
Pricing updated 2012-05-26. Prices are subject to change without notice. To ask for assistance with one of our products please contact a Technical Support Scientist. Warning This product is not for human or veterinary use. You may be eligible to receive a free sample Leptin (human) EIA Kit under the Cayman Challenge program. Let Cayman analyze your samples for you. See EIA Service for details and availability. Related ProductsShow all 7 Hide all but first 3Downloads
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins. |
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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA
Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640
Copyright 2012 Cayman Chemical Company
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