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Prostaglandin E2 FPIA Kit - Green

Cayman Chemical Item Number 500501

PGE2 Fluorescence Polarization Immunoassay - Green

Prostaglandin E2 FPIA Kit - Green

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Description

Limit of detection: 150 pg/ml · Prostaglandin E2 (PGE2) is one of the primary prostaglandins formed from the coupled metabolism of arachidonic acid by the cyclooxygenases (COX-1 and COX-2) and PGE synthases (microsomal and/or cytosolic). Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.1,2,3,4 Cayman Chemical’s PGE2 Fluorescence Polarization Immunoassay (FPIA) - Green is a break-through method for rapid, high-throughput screening of PGE2 samples. It is now possible to rapidly analyze samples and increase the rate of lead compound identification without the time-consuming incubation, washing, and development steps of a solid phase EIA.This FPIA is a homogenous, single-step assay which is easily adaptable to robotic assay systems. Simply mix the sample or standard with the assay cocktail, incubate at least 60 minutes, and read the plate whenever you are ready. Each kit contains FPIA reagent, buffer concentrate (10X), standard, 384 well plate, foil plate cover, and complete instructions.

1 Willis, A.L., and Cornelsen, M. Repeated injection of prostaglandin E2 in rat paws induces chronic swelling and a marked decrease in pain threshold. Prostaglandins 3 353-357 (1973).

2 Jackson, G.M., Sharp, H.T., and Varner, M.W. Cervical ripening before induction of labor: A randomized trial of prostaglandin E2 gel versus low-dose oxytocin. Am J Obstet Gynecol 171 1092-1096 (1994).

3 Robert, A., Schultz, J.R., Nezamis, J.E., et al. Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16,16-dimethyl PGE2. Intravenous, oral and intrajejunal administration. Gastroenterology 70 359-370 (1976).

4 Arvind, P., Papavassiliou, E.D., Tsioulias, G.J., et al. Prostaglandin E2 down-regulates the expression of HLA-DR antigen in human colon adenocarcinoma cell lines. Biochemistry 34 5604-5609 (1995).

Synonyms
  • PGE2 Fluorescence Polarization Immunoassay - Green
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Prostaglandin E1 100%
Prostaglandin E2 Ethanolamide 100%
Prostaglandin E3 85.0%
Sulprostone 9.0%
6-keto Prostaglandin F1α 2.9%
8-iso Prostaglandin F2α 0.09%
Prostaglandin D2 <0.01%
8-iso Prostaglandin E2 <0.01%
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Background Reading

Jackson, G.M., Sharp, H.T., and Varner, M.W. Cervical ripening before induction of labor: A randomized trial of prostaglandin E2 gel versus low-dose oxytocin. Am J Obstet Gynecol 171 1092-1096 (1994).

Robert, A., Schultz, J.R., Nezamis, J.E., et al. Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16,16-dimethyl PGE2. Intravenous, oral and intrajejunal administration. Gastroenterology 70 359-370 (1976).

Arvind, P., Papavassiliou, E.D., Tsioulias, G.J., et al. Prostaglandin E2 down-regulates the expression of HLA-DR antigen in human colon adenocarcinoma cell lines. Biochemistry 34 5604-5609 (1995).

Willis, A.L., and Cornelsen, M. Repeated injection of prostaglandin E2 in rat paws induces chronic swelling and a marked decrease in pain threshold. Prostaglandins 3 353-357 (1973).

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500501-96well
96-Well Solid Plate (black)
Foil Plate Covers
Prostaglandin E2 FPIA Reagent - Green 400 dtn
FPIA Buffer Concentrate (10X) 2 × 1 ea
Prostaglandin E2 FPIA Standard - Green 1 ea
500501-1920WELL
Foil Plate Covers
384-Well Solid Plate (black)
Prostaglandin E2 FPIA Reagent - Green 2000 dtn
FPIA Buffer Concentrate (10X) 4 × 1 ea
Prostaglandin E2 FPIA Standard - Green 1 ea
500501-384WELL
Foil Plate Covers
384-Well Solid Plate (black)
Prostaglandin E2 FPIA Reagent - Green 400 dtn
FPIA Buffer Concentrate (10X) 2 × 1 ea
Prostaglandin E2 FPIA Standard - Green 1 ea
Size Price Quantity Subtotal
384 wells $161.00 $0.00
1920 wells $604.00 $0.00
Bulk Contact
Cart Total $0.00

This product is also available to buy in bulk quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

You may be eligible to receive a free sample Prostaglandin E2 FPIA Kit - Green under the Cayman Challenge program.

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Let Cayman analyze your samples for you. See EIA Service for details and availability.

Is this kit right for my sample type? Prostaglandin E2 Recommendation Chart

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Prostaglandin E Metabolite EIA Kit
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UltraPure Water
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