Enterolactone is a mammalian lignan with an estrogen-like diphenolic structure. It is produced by intestinal bacteria from two plant precursors (matairesinol and secoisolariciresinol) obtained in the diet. Enterolactone and other lignans and phytoestrogens have been associated with a reduced risk of acute coronary events, hormone-dependent cancers, and possibly osteoporosis. Several studies have suggested that serum enterolactone may serve as a biomarker of a healthy, high-fiber diet. Cayman Chemical’s Enterolactone EIA kit is a competitive assay that utilizes a standard curve ranging from 15.6-2,000 pg/ml. The assay exhibits an IC₅₀ (50% B/B₀) of 240 pg/ml and an IC₈₀ (defined as 80% B/B₀) of 70 pg/ml.

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