Prostaglandin Screening EIA Kit
Cayman Chemical Item Number 514012
Prostaglandin Screening ELISA Kit; PG Screening EIA Kit
Prostaglandin Screening EIA Kit
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Description
Limit of detection:
80% B/B0: 29 pg/ml
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Sensitivity:
50% B/B0: 222 pg/ml
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This assay was developed for screening applications in which the relative amount of prostaglandin (PG) production for a large number of cell culture samples must be determined. Our PGE2 assay (Item No. 514010) is unparalleled in sensitivity and specificity, but the steep standard curve can make screening many samples tedious. The specificity of the PGE2 assay also eliminates quantification of other PGs which may be produced by the cells. The antiserum used in this assay exhibits high cross reactivity for most PGs which will allow quantification of all the PGs in a given sample with a single assay. The broad standard curve minimizes the need for sample dilution. Because this assay will also recognize thromboxane B2 (TXB2), cell culture media must not contain fetal calf serum (FCS). The high concentration of TXB2 in serum (approximately 400 ng/ml) will completely displace the tracer, making PG measurement impossible.
| Synonyms |
- Prostaglandin Screening ELISA Kit
- PG Screening EIA Kit
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| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
Wet ice
in continental US; may vary elsewhere
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| Specificity |
| Prostaglandin E1 |
100% |
| Prostaglandin E2 |
100% |
| Prostaglandin F1α |
100% |
| Prostaglandin F2α |
100% |
| Prostaglandin F3α |
51.3% |
| Prostaglandin E2 Ethanolamide |
44.0% |
| 6-keto Prostaglandin F1α |
43.6% |
| 8-iso Prostaglandin F2α |
38.4% |
| 8-iso Prostaglandin E2 |
28.5% |
| Prostaglandin D2 |
26.6% |
| 8-iso-2,3-dinor Prostaglandin F1α |
20.0% |
| Prostaglandin E3 |
9.5% |
| Thromboxane B2 |
5.0% |
| 12(S)-HHTrE |
0.25% |
| Leukotriene D4 |
0.2% |
| Arachidonic Acid |
<0.01% |
| Leukotriene B4 |
<0.01% |
| Leukotriene C4 |
<0.01% |
| Leukotriene E4 |
<0.01% |
| Misoprostol |
<0.01% |
| Misoprostol (free acid) |
<0.01% |
| Prostaglandin A1 |
<0.01% |
| Prostaglandin A2 |
<0.01% |
| Prostaglandin A3 |
<0.01% |
| Prostaglandin B1 |
<0.01% |
| 15-keto Prostaglandin E2 |
<0.01% |
| 13,14-dihydro-15-keto Prostaglandin F2α |
<0.01% |
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Background Reading
Maxey, K.M., Maddipati, K.R., and Birkmeier, J. Interference in enzyme immunoassays. J Clin Immunoassay 15 116-120 (1992).
Pradelles, P., Grassi, J., and Maclouf, J.A. Enzyme immunoassays of eicosanoids using acetylcholinesterase as label: An alternative to radioimmunoassay. Anal Chem 57 1170-1173 (1985).
Maclouf, J., Grassi, J., and Pradelles, P. Development of enzyme-immunoassay techniques for the measurement of eicosanoids. 355-364 (1987).
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- All 480 well kits are supplied with a single 500 dtn vial of tracer and antiserum that must be used within the stated time following reconstitution.
- Check the Additional Items Required section of this kit booklet to verify if UltraPure Water (Milli-Q or equivalent) is needed for this assay.
Pricing updated 2012-02-12.
Prices are subject to change without notice.
To ask for assistance with one of our products please contact a Technical Support Scientist.
Warning This product is not for human or veterinary use.
You may be eligible to receive a free sample Prostaglandin Screening EIA Kit under the Cayman Challenge program.
Let Cayman analyze your samples for you. See EIA Service for details and availability.
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Batch-specific Information
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.
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