Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

COX (ovine) Inhibitor Screening Assay Kit

Cayman Chemical Item Number 560101

COX (ovine) Inhibitor Screening Assay Kit

See more	Inhibitor Screening Assay (33) Assay Kits (320) Cyclooxygenase (97) Eicosanoids (216) Drug Discovery (76)

Description

The COX (ovine) Inhibitor Screening Assay directly measures PGF_2α produced in the cyclooxygenase reaction. The prostanoid product is quantified via enzyme immunoassay (EIA) using a broadly specific antibody that binds to all the major prostaglandin compounds. Thus, this Cayman COX assay is more accurate and reliable than an assay based on peroxidase inhibition. The Cayman COX (ovine) Inhibitor Screening Assay includes both ovine COX-1 and COX-2 enzymes in order to screen isozyme-specific inhibitors. This assay is an excellent tool which can be used for general inhibitor screening, or to eliminate false positive leads generated by less specific methods.

Stability

1 year

Storage

-80°C

Shipping

Dry ice in continental US; may vary elsewhere

Specificity

Prostaglandin E1	100%
Prostaglandin E2	100%
Prostaglandin F1α	100%
Prostaglandin F2α	100%
Prostaglandin F3α	51.3%
Prostaglandin E2 Ethanolamide	44.0%
6-keto Prostaglandin F1α	43.6%
8-iso Prostaglandin F2α	38.4%
8-iso Prostaglandin E2	28.5%
Prostaglandin D2	26.6%
8-iso-2,3-dinor Prostaglandin F1α	20.0%
Prostaglandin E3	9.5%
Thromboxane B2	5.0%
12(S)-HHTrE	0.25%
Leukotriene D4	0.2%
Arachidonic Acid	<0.01%
Leukotriene B4	<0.01%
Leukotriene C4	<0.01%
Leukotriene E4	<0.01%
Misoprostol	<0.01%
Misoprostol (free acid)	<0.01%
Prostaglandin A1	<0.01%
Prostaglandin A2	<0.01%
Prostaglandin A3	<0.01%
Prostaglandin B1	<0.01%
15-keto Prostaglandin E2	<0.01%
13,14-dihydro-15-keto Prostaglandin F2α	<0.01%

Show all 27 Hide all but first 3

560101-96WELL
Precoated (Mouse Anti-Rabbit IgG) EIA 96-Well Strip Plate	1 ea
Polysorbate 20	1 ea
Ellman's Reagent	3 × 100 dtn
EIA Buffer Concentrate (10X)	2 × 10 mL
Wash Buffer Concentrate (400X)	5 mL
Prostaglandin Screening AChE Tracer	100 dtn
Prostaglandin Screening EIA Antiserum	100 dtn
Prostaglandin Screening EIA Standard	1 ea
COX Inhibitor Screening Assay COX-1 (ovine)	1 ea
COX Inhibitor Screening Assay COX-2 (ovine)	1 ea
COX Inhibitor Screening Assay Heme	1 ea
COX Inhibitor Screening Assay Arachidonic Acid (substrate)	1 ea
COX Inhibitor Screening Assay Reaction Buffer (10X)	1 ea
COX Inhibitor Screening Assay Potassium Hydroxide	1 ea
COX Inhibitor Screening Assay Hydrochloric Acid	1 ea
COX Inhibitor Screening Assay Stannous Chloride	1 ea

Size	Price	Quantity	Subtotal
96 wells	$371.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

You may be eligible to receive a free sample COX (ovine) Inhibitor Screening Assay Kit under the Cayman Challenge program.

Related Products

Show all 20 Hide all but first 3

Downloads

	Download Kit Booklet 748 Kb PDF
	Download Material Safety Data Sheet (MSDS) 498 Kb PDF
	Printer-friendly version of this page small PDF (usually less than 100 Kb)
	• US Letter paper 8½″ × 11″
	• A4 paper 21cm × 29.7cm
	Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Batch-specific Information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs	Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases	Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule	Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

COX (ovine) Inhibitor Screening Assay Kit

COX (ovine) Inhibitor Screening Assay Kit

Description

Related Products

Downloads

Batch-specific Information

Quick Search