|
582281 Estriol EIA Kit
Estriol ELISA Kit
Estriol EIA Kit Workbook Links
Cayman offers a variety of analysis tools to assist you.
Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
You may be eligible to receive a free sample Estriol EIA Kit under the Cayman Challenge program.
Let Cayman analyze your samples for you. See EIA Service for details and availability.
|
Limit of detection:
80% B/B0: 4 pg/ml (4°C for 18 hours) 14 pg/ml (RT for 2 hours)
·
Sensitivity:
50% B/B0: 33 pg/ml (4°C for 18 hours) 95 pg/ml (RT for 2 hours)
·
Estriol, a metabolite of 17β-estradiol and a major estrogen produced during pregnancy, has historically been used as an indicator of fetal well-being. In the final weeks before parturition, estriol levels increase significantly. In a longitudinal study in healthy pregnant women, total plasma estriol levels increased from <10 ng/ml at 8-10 weeks gestation to approximately 150 ng/ml at week 38.1 The majority of the estriol synthesized in the later stages of pregnancy originates from fetal dehydroepiandrosterone sulfate (DHEAS) and serves as a direct marker of fetal adrenal gland activity.2 In the 1960s and 1970s plasma and urine were used to measure estriol. However, saliva contains primarily unbound and unconjugated estriol, the biologically active form of the hormone, and therefore is currently a commonly used biological fluid for monitoring estriol levels.2,3 Plasma levels of estriol in males and non-pregnant females is less than 2 ng/ml.4
|
|
1
Peter, M., Dörr, H.G., Sippell, W.G. Changes in the concentrations of dehydroepiandrosterone sulfate and estriol in maternal plasma during pregnancy: A longitudinal study in healthy women throughout gestation and at term. Horm Res 42 278-281 (1994).
2
Goodwin, T.M. A role for estriol in human labor, term and preterm. Am J Obstet Gynecol 180 S208-S213 (1999).
3
Voss, H.F. Hormonal pathways of preterm birth. Am J Obstet Gynecol 180 S226-S231 (1999).
4
Steroid levels in humans. (1999 Apr 19).
|
Purchase 582281 Estriol EIA Kit
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
Please contact our
Sales Department
for a quote or to purchase.
Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services.
To ask for assistance with one of our products please contact our Technical Help staff.
Warning This product is not for human or veterinary use.
|
Pricing updated 2010-03-20.
Prices are subject to change without notice.
|
|
Many of our kits require a source of UltraPure Water. If you do not have a source it is available for purchase from Cayman Chemical. Please check the Additional Items Required section of this kit booklet to verify if Ultra Pure Water is needed.
Please note that the 480 well kits are supplied with a single 500 dtn vial of tracer and antiserum that must be used within the stated time following reconstitution. Please see the individual kit booklets for these details or contact techserv@caymanchem.com.
|
|
|
