Vasopressin EIA Kit; AVP ELISA Kit; Antidiuretic Hormone (ADH) EIA Kit; Argipressin EIA Kit

Click image to enlarge

Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

You may be eligible to receive a free sample Arginine Vasopressin EIA Kit under the Cayman Challenge program.

Let Cayman analyze your samples for you. See EIA Service for details and availability.

Arginine vasopressin (AVP), also known as argipressin, antidiuretic hormone (ADH), or simply as vasopressin, is a nine amino acid peptide hormone that plays a primary role in the regulation of renal water excretion and a secondary role in the regulation of cardiovascular function in mammals.1,2,3 AVP acts on epithelial cells of the urinary tract to augment the reabsorption of water, resulting in concentration of urine and dilution of blood serum. It also stimulates the constriction of capillaries and arterioles, elevating blood pressure.4 Normal levels of AVP in serum are 0.4-5.2 pg/ml.5,6 Plasma levels of AVP are elevated in patients with major and also anxious-retarded depression, as well as in patients with congestive heart failure.5,7,8,9 Cayman’s AVP EIA is a competitive assay that can be used for the measurement of AVP from plasma and serum. The assay is characterized by an IC50 (50% B/B0) value of ~220-380 pg/ml and an IC80 (80% B/B0) value of ~45-60 pg/ml.

1  Brownstein, M.J., Russell, J.T., Gainer, H. Synthesis, transport, and release of posterior pituitary hormones. Science 207 373-378 (1980). 2  Robertson, G.L., Berl, T. Pathophysiology of water metabolism. 4th, 677-736 (1991). 3  St-Louis, J., Schiffrin, E.L. Biological action and binding sites for vasopressin on the mesenteric artery from normal and sodium-depleted rats. Life Sci 35 1489-1495 (1984). 4  Thionnier, M. Signal transduction of V1-vascular vasopressin receptors. Regul Pept 38 1-11 (1992). 5  van Londen, L., Goekoop, J.G., van Kempen, G.M., et al. Plasma levels of arginine vasopressin elevated in patients with major depression. Neuropsychoparmacology 17 284-292 (1997). 6  Robertson, G.L., Mahr, E.A., Athar, S., et al. Development and clinical application of a new method for the radioimmunoassay of arginine vasopressin in human plasma. J Clin Invest 52 2340-2352 (1973). 7  de Winter, R.F.P., van Hemert, A.M., DeRijk, R.H., et al. Anxious-retarded depression: Relation with plasma vasopressin and cortisol. Neuropsychoparmacology 23 140-147 (2003). 8  Creager, M.A., Faxon, D.P., Cutler, S.S., et al. Contribution of vasopressin to vasoconstriction in patients with congestive heart failure: Comparison with the renin-angiotensin system and the sympathetic nervous system. J Am Coll Cardiol 7 758-765 (1986). 9  Price, J.F., Towbin, J.A., Denfield, S.W., et al. Arginine vasopressin levels are elevated and correlate with functional status in infants and children with congestive heart failure. Circulation 109 2550-2553 (2004).

	Download Kit Booklet 682 Kb PDF
	Download Abbreviated Kit Protocol 418 Kb PDF
	Download Material Safety Data Sheet (MSDS) 151 Kb PDF
	Printer-friendly version of this page small PDF (usually less than 100 Kb)
	• US Letter paper 8½″ × 11″
	• A4 paper 21cm × 29.7cm

Many of our kits require a source of UltraPure Water. If you do not have a source it is available for purchase from Cayman Chemical. Please check the Additional Items Required section of this kit booklet to verify if Ultra Pure Water is needed. Please note that the 480 well kits are supplied with a single 500 dtn vial of tracer and antiserum that must be used within the stated time following reconstitution. Please see the individual kit booklets for these details or contact techserv@caymanchem.com.