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Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.
sPLA2 (human Type IIA) EIA KitCayman Chemical Item Number 585000 sPLA2 (human Type IIa) ELISA Kit; Secretory Phospholipase A2 (human synovial) EIA Kit 
sPLA2 (human Type IIA) EIA Kit
sPLA2 (human Type IIA) EIA Kit Analysis ToolsCayman offers a variety of analysis tools to assist you.
Description
Limit of detection:
15 pg/ml
·
sPLA2 are found in the venom of certain snakes (Types IA, IIA, and IIB from vipers, cobras, rattlesnakes, and kraits), in pancreatic juices (Type IB), in rat and murine testes (Type IIC), in placenta, synovial fluids and platelets (Type IIA), and in heart, placenta, lung, mast cells and P388D1 macrophages (Type V).1 Until 1994 the sPLA2 responsible for the release of arachidonic acid in inflammation was believed to be Type IIA. Although recently discovered isoforms of PLA2 clearly contribute to the release of arachidonic acid, sPLA2 (Type IIA) continues to be a protein of interest in the field of inflammation. This EIA is specific for Type IIA sPLA2, and does not crossreact with Type I, Type IV or Type V PLA2, or inflammatory mediators such as tumor necrosis factor, interleukin-
1 Dennis, E.A. The growing phospholipase A2 superfamily of signal transduction enzymes. Trends Biochem Sci 22 1-2 (1997).
Background ReadingGrassi, J., Roberge, C.J., Frobert, Y., et al. Determination of IL1α, IL1β and IL2 in biological media using specific enzyme immunometric assays. Immunol Rev 119 125-142 (1991). Dennis, E.A. The growing phospholipase A2 superfamily of signal transduction enzymes. Trends Biochem Sci 22 1-2 (1997). Tischfield, J.A. A reassessment of the low molecular weight phospholipase A2 gene family in mammals. J Biol Chem 272 17247-17250 (1997). |
This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase. Pricing updated 2012-05-26. Prices are subject to change without notice. To ask for assistance with one of our products please contact a Technical Support Scientist. Warning This product is not for human or veterinary use. You may be eligible to receive a free sample sPLA2 (human Type IIA) EIA Kit under the Cayman Challenge program. Let Cayman analyze your samples for you. See EIA Service for details and availability. Related ProductsShow all 8 Hide all but first 3Downloads
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins. |
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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA
Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640
Copyright 2012 Cayman Chemical Company
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