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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

CGRP (rat) EIA Kit

Cayman Chemical Item Number 589001

Calcitonin Gene-Related Peptide (rat) EIA Kit; CGRP (rat) ELISA Kit

CGRP (rat) EIA Kit

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CGRP (rat) EIA Kit Analysis Tools

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Description

Limit of detection: <1 pg/ml · CGRP is a 37 amino acid peptide synthesized in the central and peripheral nervous system from a calcitonin/CGRP gene complex. Two isoforms have been described which differ by three amino acids and display similar biological activities: CGRP-α, which is produced by alternative splicing of a calcitonin gene transcript, and CGRP-β, the product of a separate gene. In the CNS, CGRP acts as a neurotransmitter that is released from a subset of small sensory neurons that transmit pain information. In the circulation, CGRP is one of the most potent vasodilators known and may function as a regulator of blood flow. When administered systemically, CGRP causes hypotension in several species, including humans. Intradermal administration of CGRP at femtomole doses produces increased blood flow and persistent reddening. This EIA is based on a double-antibody sandwich technique that permits measurement of CGRP within the range of 0-500 pg/ml, with a detection limit of <1 pg/ml. This assay provides a method for the sensitive, specific analysis of CGRP in a variety of samples including plasma, serum, nervous tissue, CSF, and culture media.
Synonyms
  • Calcitonin Gene-Related Peptide (rat) EIA Kit
  • CGRP (rat) ELISA Kit
Stability 6 months
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
rat CGRP-α 100%
rat CGRP-β 100%
human CGRP-α 83%
human CGRP-β 83%
Amylin <0.01%
Calcitonin <0.01%
CGRP (8-37) <0.01%
Substance P <0.01%
Show all 8 Hide all but first 3

Background Reading

Zaidi, M., Bevis, P.J.R., Abeyasekera, G., et al. The origin of circulating calcitonin gene-related peptide in the rat. J Endocrinol 110 185-190 (1986).

Brain, S.D., Williams, T.J., Tippins, J.R., et al. Calcitonin gene-related peptide is a potent vasodilator. Nature 313 54-56 (1985).
Size Price Quantity Subtotal
1 ea $391.00 $0.00
Bulk Contact
Cart Total $0.00

This product is also available to buy in bulk quantities.

Please contact our Sales Department for a quote or to purchase.

  • All 480 well kits are supplied with a single 500 dtn vial of tracer and antiserum that must be used within the stated time following reconstitution.
  • Check the Additional Items Required section of this kit booklet to verify if UltraPure Water (Milli-Q or equivalent) is needed for this assay.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

You may be eligible to receive a free sample CGRP (rat) EIA Kit under the Cayman Challenge program.

Let Cayman analyze your samples for you. See EIA Service for details and availability.

Related Products

CGRP Affinity Sorbent
CGRP (human) EIA Kit

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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

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