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Eicosapentaenoyl PAF C-16

Cayman Chemical Item Number 60907

(CAS 132196-28-2)

Eicosapentaenoyl PAF C-16 (CAS 132196-28-2)

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Description

Eicosapentaenoyl PAF C-16 can be formed by incorporation of eicosapentaenoic acid (EPA) into lyso-PAF C-16, as has been demonstrated using neutrophils from monkeys and humans fed a diet enriched in fish oils.1,2 Eicosapentaenoyl PAF C-16 can serve as a substrate for PAF C-16 formation by the remodeling pathway.2

1 Chabot, M.C., Schmitt, J.D., Bullock, B.C., et al. Reacylation of platelet activating factor with eicosapentaenoic acid in fish-oil-enriched monkey neutrophils. Biochim Biophys Acta 922 214-220 (1987).

2 Triggiani, M., Connell, T.R., and Chilton, F.H. Evidence that increasing the cellular content of eicosapentaenoic acid does not reduce the biosynthesis of platelet-activating factor. J Immunol 145 2241-2248 (1990).

Formal Name 1-​O-​hexadecyl-​2-​O-​(5Z,​8Z,​11Z,​14Z,​17Z-​eicosapentaenoyl)-​sn-​glyceryl-​3-​phosphorylcholine
CAS Number 132196-28-2
Molecular Formula C44H80NO7P
Formula Weight 766.1
Formulation Solution in ethanol with 0.1% BHT
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCCOC[C@H]​(COP(=O)​(O)​OCC[N]​(C)​(C)​C)​OC(=O)​CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC

Background Reading

Triggiani, M., Connell, T.R., and Chilton, F.H. Evidence that increasing the cellular content of eicosapentaenoic acid does not reduce the biosynthesis of platelet-activating factor. J Immunol 145 2241-2248 (1990).

Chabot, M.C., Schmitt, J.D., Bullock, B.C., et al. Reacylation of platelet activating factor with eicosapentaenoic acid in fish-oil-enriched monkey neutrophils. Biochim Biophys Acta 922 214-220 (1987).

Eicosapentaenoyl PAF C-16 is available in the following screening library:

Size Price Quantity Subtotal
1 mg $43.00 $0.00
5 mg $194.00 $0.00
10 mg $344.00 $0.00
50 mg $1,505.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

Docosahexaenoyl PAF C-16
Eicosapentaenoyl Ethanolamide
PAF C-16

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