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Pyrrolidino PAF C-16

Cayman Chemical Item Number 60909

(CAS 91021-63-5)

Pyrrolidino PAF C-16 (CAS 91021-63-5)

See more	Lipids (167) Phospholipase (79)

Description

Pyrrolidino PAF C-16 is a synthetic analog of PAF C-16. It is a potent mediator of PAF-like activities, including hypotension^1,2 and platelet aggregation, where it is approximately 3-10 times more potent than PAF itself.^1,2

1 Shigenobu, K., Masuda, Y., Tanaka, Y., et al. Platelet activating factor analogues: Lack of correlation between their activities to produce hypotension and endothelium-mediated vasodilation. J Pharmacobiodyn 8 128-133 (1985).

2 Kasuya, Y., Masuda, Y., and Shigenobu, K. Hypotensive actions of some analogues of platelet-activating factor (PAF) with higher potencies than natural PAF. Can J Physiol Pharmacol 62 457-459 (1984).

Formal Name	1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphoryl-N-methyl-pyrrolidinium ethanol
CAS Number	91021-63-5
Molecular Formula	C₂₈H₅₆NO₇P
Formula Weight	549.7
Formulation	A lyophilized powder
Purity	>98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N]1(C)CCCC1)OC(=O)C

Background Reading

Kasuya, Y., Masuda, Y., and Shigenobu, K. Hypotensive actions of some analogues of platelet-activating factor (PAF) with higher potencies than natural PAF. Can J Physiol Pharmacol 62 457-459 (1984).

Shigenobu, K., Masuda, Y., Tanaka, Y., et al. Platelet activating factor analogues: Lack of correlation between their activities to produce hypotension and endothelium-mediated vasodilation. J Pharmacobiodyn 8 128-133 (1985).

Pyrrolidino PAF C-16 is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
1 mg	$43.00		$0.00
5 mg	$194.00		$0.00
10 mg	$344.00		$0.00
50 mg	$1,505.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Related Products

PAF C-16

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