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Hexadecyl Acetyl Glycerol

Cayman Chemical Item Number 60920

HAG (CAS 77133-35-8)

Hexadecyl Acetyl Glycerol (CAS 77133-35-8)

See more	Lipids (167)

Description

Hexadecyl acetyl glycerol (HAG) is an analog of DAG, which inhibits the activation of PKC by DAG.¹ It also inhibits the growth of HL-60 cells and induces differentiation to cells resembling mononuclear phagocytes. Following treatment with 5 µg/ml HAG for six days, HL-60 cells demonstrated a 10-fold increase in non-specific esterase activity.²

1 Daniel, L.W., Small, G.W., and Schmitt, J.D. Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols. Biochem Biophys Res Commun 151 291-297 (1988).

2 McNamara, M.J.C., Schmitt, J.D., Wykle, R.L., et al. 1-O-Hexadecyl-2-acetyl-sn-glycerol stimulates differentiation of HL-60 human promyelocytic leukemia cells to macrophage-like cells. Biochem Biophys Res Commun 122 824-830 (1984).

Synonyms	HAG
Formal Name	1-O-hexadecyl-2-O-acetyl-sn-glycerol
CAS Number	77133-35-8
Molecular Formula	C₂₁H₄₂O₄
Formula Weight	358.6
Formulation	A solution in acetonitrile
Purity	≥90%
Stability	6 months
Storage	-80°C
Shipping	Dry ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCCCCCCCCCCOC[C@H](CO)OC(=O)C

Background Reading

McNamara, M.J.C., Schmitt, J.D., Wykle, R.L., et al. 1-O-Hexadecyl-2-acetyl-sn-glycerol stimulates differentiation of HL-60 human promyelocytic leukemia cells to macrophage-like cells. Biochem Biophys Res Commun 122 824-830 (1984).

Daniel, L.W., Small, G.W., and Schmitt, J.D. Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols. Biochem Biophys Res Commun 151 291-297 (1988).

Hexadecyl Acetyl Glycerol is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
5 mg	$39.00		$0.00
10 mg	$74.00		$0.00
50 mg	$312.00		$0.00
100 mg	$546.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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