1 Street, I.P., Lin, H., Laliberté, F., et al. Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A₂. Biochemistry 32 5935-5940 (1993).

2 Ackermann, E.J., Conde-Frieboes, K., and Dennis, E.A. Inhibition of macrophage Ca2+-independent phospholipase A₂ by bromoenol lactone and trifluoromethyl ketones. J Biol Chem 270 445-450 (1995).

3 Conde-Frieboes, K., Reynolds, L.J., Lio, Y., et al. Activated ketones as inhibitors of intracellular Ca2+-dependent and Ca2+-independent phospholipase A₂. J Am Chem Soc 118 5519-5525 (1996).

4 Bartoli, F., Lin, H., Ghomashchi, F., et al. Tight binding inhibitors of 85-kDa phospholipase A₂ but not 14-kDa phospholipase A₂ inhibit release of free arachidonate in thrombin-stimulated human platelets. J Biol Chem 269 15625-15630 (1994).

5 Riendeau, D., Guay, J., Weech, P.K., et al. Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A₂, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. J Biol Chem 269 15619-15624 (1994).

Street, I.P., Lin, H., Laliberté, F., et al. Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A₂. Biochemistry 32 5935-5940 (1993).

Bartoli, F., Lin, H., Ghomashchi, F., et al. Tight binding inhibitors of 85-kDa phospholipase A₂ but not 14-kDa phospholipase A₂ inhibit release of free arachidonate in thrombin-stimulated human platelets. J Biol Chem 269 15625-15630 (1994).

Conde-Frieboes, K., Reynolds, L.J., Lio, Y., et al. Activated ketones as inhibitors of intracellular Ca2+-dependent and Ca2+-independent phospholipase A₂. J Am Chem Soc 118 5519-5525 (1996).

Riendeau, D., Guay, J., Weech, P.K., et al. Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A₂, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. J Biol Chem 269 15619-15624 (1994).

Ackermann, E.J., Conde-Frieboes, K., and Dennis, E.A. Inhibition of macrophage Ca2+-independent phospholipase A₂ by bromoenol lactone and trifluoromethyl ketones. J Biol Chem 270 445-450 (1995).

Arachidonyl Trifluoromethyl Ketone is available in the following screening library:

• Bio-active Lipid I Screening Library (96-Well)