See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Diphenyl-1-pyrenylphosphine

Cayman Chemical Item Number 62237

DPPP (CAS 110231-30-6)

Diphenyl-1-pyrenylphosphine (CAS 110231-30-6)

See more

Description

Diphenyl-1-pyrenylphosphine (DPPP) is a probe that reacts stoichiometrically with hydroperoxides to yield the fluorescent molecule diphenyl-1-pyrenylphosphine oxide (DPPP-O).1 Plasma levels of lipid hydroperoxides of phosphatidylcholine, phosphatidylethanolamine, triglycerides, and cholesteryl esters have been measured by HPLC with a post column detection system using DPPP.2,3 DPPP has also been used as a fluorescent probe for the detection of low density lipoprotein and cellular oxidation.4 Fluorescence of DPPP-O can be monitor using excitation and emission wavelengths of 351 nm and 380 nm, respectively.

1 Okimoto, Y., Watanabe, A., Niki, E., et al. A novel fluorescent probe diphenyl-1-pyrenylphosphine to follow lipid peroxidation in cell membranes. FEBS Lett 474 137-140 (2000).

2 Alasaka, K., Ijichi, S., Watanabe, K., et al. High performance liquid chromatography and post column derivatization with DPPP for fluorometric determination of triglycerol hydropeoxides. J Chromatogr 596 197-202 (1992).

3 Akassaka, K., Ijichi, S., Ohrui, H., et al. Simultaneous determination of hydroperoxides of phosphotidylcholine, cholesterol esters and triglycerols by column-switiching HPLC witha postcolumn detection system. J Chromatogr 622 153-159 (1993).

4 Okimoto, Y., Warabi, E., Wada, Y., et al. A novel method of following oxidation of low-density lipoprotein using a sensitive fluorescent probe, diphenyl-1-pyrenylphosphine. Free Radic Biol Med 35(6) 576-585 (2003).

Synonyms
  • DPPP
Formal Name diphenyl-​1-​pyrenylphosphine
CAS Number 110231-30-6
Molecular Formula C28H19P
Formula Weight 386.4
Formulation A crystalline solid
Purity ≥98%
λmax 243, 280, 355 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
c1ccc(cc1)​P(c1ccccc1)​c1ccc2ccc3cccc4ccc1c2c34

Background Reading

Okimoto, Y., Watanabe, A., Niki, E., et al. A novel fluorescent probe diphenyl-1-pyrenylphosphine to follow lipid peroxidation in cell membranes. FEBS Lett 474 137-140 (2000).

Alasaka, K., Ijichi, S., Watanabe, K., et al. High performance liquid chromatography and post column derivatization with DPPP for fluorometric determination of triglycerol hydropeoxides. J Chromatogr 596 197-202 (1992).

Akassaka, K., Ijichi, S., Ohrui, H., et al. Simultaneous determination of hydroperoxides of phosphotidylcholine, cholesterol esters and triglycerols by column-switiching HPLC witha postcolumn detection system. J Chromatogr 622 153-159 (1993).
Size Price Quantity Subtotal
5 mg $132.00 $0.00
10 mg $251.00 $0.00
25 mg $594.00 $0.00
50 mg $1,056.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

2,7-Dichlorodihydrofluorescein diacetate
Antioxidant Assay Kit
APF
DAF-2 diacetate
Dihydrorhodamine 123
HPF
Lipid Hydroperoxide (LPO) Assay Kit
Pentafluorobenzenesulfonyl fluorescein
Show all 8 Hide all but first 3

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?