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10-Pyrene-PC

Cayman Chemical Item Number 62245

1-Palmitoyl-2-pyrenedecanoyl Phosphatidylcholine (CAS 95864-17-8)

10-Pyrene-PC (CAS 95864-17-8)

See more	Lipids (167) Phospholipase (79)

Description

10-Pyrene-PC is a substrate for all PLA₂s with the exception of cPLA₂ and PAF-AH.¹ Upon phospholipid hydrolysis, 10-pyrenyldecanoic acid is produced from 10-pyrene-PC. The monomeric 10-pyrenyldecanoic acid exhibits fluorescence (excitation 345 nm, emission 395 nm), allowing quantitation of phospholipase activity.²

1 Roberts, M.F. Phospholipases: Structural and functional motifs for working at an interface. FASEB J 10 1159-1172 (1996).

2 Lusa, S., Myllärniemi, M., Volmonen, K., et al. Degradation of pyrene-labelled phospholipids by lysosomal phospholipases in vitro. Dependence of degradation on the length and position of the labelled and unlabelled acyl chains. Biochem J 315 947-952 (1996).

Synonyms	1-Palmitoyl-2-pyrenedecanoyl Phosphatidylcholine
Formal Name	1-O-hexadecanoyl-2-O-(10-(1-pyrenyl)decanoyl)-sn-glyceryl-3-phosphorylcholine
CAS Number	95864-17-8
Molecular Formula	C₅₀H₇₆NO₈P
Formula Weight	850.1
Formulation	A solution in chloroform
Purity	>98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N](C)(C)C)OC(=O)CCCCCCCCCc1cc2ccc3cccc4ccc(c1)c2c34

Background Reading

Lusa, S., Myllärniemi, M., Volmonen, K., et al. Degradation of pyrene-labelled phospholipids by lysosomal phospholipases in vitro. Dependence of degradation on the length and position of the labelled and unlabelled acyl chains. Biochem J 315 947-952 (1996).

Roberts, M.F. Phospholipases: Structural and functional motifs for working at an interface. FASEB J 10 1159-1172 (1996).

Size	Price	Quantity	Subtotal
1 mg	$122.00		$0.00
5 mg	$549.00		$0.00
10 mg	$976.00		$0.00
25 mg	$2,135.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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