See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

7-hydroxycoumarinyl Arachidonate Exclusive

Cayman Chemical Item Number 62910

Umbelliferyl Arachidonate (CAS 161180-11-6)

7-hydroxycoumarinyl Arachidonate (CAS 161180-11-6)

See more

Description

7-hydroxycoumarinyl Arachidonate is the arachidonic acid ester of 7-hydroxycoumarin (umbelliferone) and behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl arachidonate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm).1,2

1 Huang, Z., Laliberté, F., Tremblay, N.M., et al. A continuous fluorescence-based assay for the human high-molecular-weight cytosolic phospholipase A2. Anal Biochem 222 110-115 (1994).

2 Pickard, R.T., Chiou, X.G., Strifler, B.A., et al. Identification of essential residues for the catalytic function of 85-kDa cytosolic phospholipase A2. Probing the role of histidine, aspartic acid, cysteine, and arginine. J Biol Chem 271 19225-19231 (1996).

Synonyms
  • Umbelliferyl Arachidonate
Formal Name 5Z,​8Z,​11Z,​14Z-​eicosatetraenoic acid,​ 2-​oxo-​2H-​1-​benzopyran-​7-​yl ester
CAS Number 161180-11-6
Molecular Formula C29H36O4
Formula Weight 448.6
Formulation A solution in ethanol
Purity ≥98%
λmax 282, 312 nm
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)​Oc1ccc2ccc(=O)​oc2c1

Background Reading

Huang, Z., Laliberté, F., Tremblay, N.M., et al. A continuous fluorescence-based assay for the human high-molecular-weight cytosolic phospholipase A2. Anal Biochem 222 110-115 (1994).

Pickard, R.T., Chiou, X.G., Strifler, B.A., et al. Identification of essential residues for the catalytic function of 85-kDa cytosolic phospholipase A2. Probing the role of histidine, aspartic acid, cysteine, and arginine. J Biol Chem 271 19225-19231 (1996).

7-hydroxycoumarinyl Arachidonate is available in the following screening library:

Size Price Quantity Subtotal
5 mg $28.00 $0.00
10 mg $53.00 $0.00
25 mg $126.00 $0.00
50 mg $224.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

10-Pyrene-PC
1,2-bis(heptanoylthio) Glycerophosphocholine
7-hydroxycoumarinyl-γ-Linolenate
cis-Parinaric Acid
cPLA2 Assay Kit
Show all 5 Hide all but first 3

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?