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PtdIns-(3,4)-P2 (1,2-dipalmitoyl) (sodium salt)

Cayman Chemical Item Number 64922

Phosphatidylinositol-3,4-diphosphate C-16; DPPI-3,4-P2

PtdIns-(3,4)-P2 (1,2-dipalmitoyl) (sodium salt)

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Description

The phosphatidylinositols (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns is phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PIP2 by PI-specific phospholipase C generates IP3 and diacylglycerol (DAG). The DAG and IP3 produced by this reaction are part of a complex biochemical and signal transduction cascade that is at the frontier of scientific research today.

1 Lapetina, E.G., Billah, M.M., and Cuatrecasas, P. The phosphatidylinositol cycle and the regulation of arachidonic acid production. Nature 292 367-369 (1981).

2 Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

Synonyms
  • Phosphatidylinositol-3,4-diphosphate C-16
  • DPPI-3,4-P2
Formal Name 1-​(1,​2R-​dihexadecanoylphosphatidyl)inositol-​3,​4-​bisphosphate,​ trisodium salt
Molecular Formula C41H78O19P3 · 3Na
Formula Weight 1036.9
Formulation A lyophilized powder
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCC(OC[C@H]​(COP(O[C@@H]​1[C@H]​(O)​[C@H]​(OP([O-]​)​(O)​=O)​[C@@H]​(OP([O-]​)​(O)​=O)​[C@H]​(O)​[C@H]​1O)​([O-]​)​=O)​OC(CCCCCCCCCCCCCCC)​=O)​=O.[3Na]​

Background Reading

Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

Lapetina, E.G., Billah, M.M., and Cuatrecasas, P. The phosphatidylinositol cycle and the regulation of arachidonic acid production. Nature 292 367-369 (1981).

PtdIns-(3,4)-P2 (1,2-dipalmitoyl) (sodium salt) is available in the following screening library:

Size Price Quantity Subtotal
100 µg $38.00 $0.00
500 µg $171.00 $0.00
1 mg $304.00 $0.00
5 mg $1,330.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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