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PtdIns-(5)-P₁ (1,2-dipalmitoyl) (ammonium salt)

Cayman Chemical Item Number 64925

DPPI-5-P₁ (ammonium salt)

PtdIns-(5)-P1 (1,2-dipalmitoyl) (ammonium salt)

See more	Inositol Phosphates (78) Lipids (167)

Description

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.^1,2 PtdIns-(5)-P₁ can be further phosphorylated to give diphosphates such as PtdIns-(4,5)-P₂. These can also be cleaved by PI-specific phospholipase C (PLC) to give inositol triphosphates (IP₃). The diacyl glycerol and IP₃ generated by this PLC-cleavage are also part of a complex biochemical and signal transduction cascade which has not been entirely elucidated. For some additional reading, please see references ^2,3,4.

1 Lapetina, E.G., Billah, M.M., and Cuatrecasas, P. The phosphatidylinositol cycle and the regulation of arachidonic acid production. Nature 292 367-369 (1981).

2 Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

3 Pike, L.J., and Casey, L. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains. J Biol Chem 271 26453-26456 (1996).

4 Berridge, M.J. Inositol trisphosphate and calcium signalling. Nature 361 315-325 (1993).

Synonyms	DPPI-5-P1 (ammonium salt)
Formal Name	1-(1,2-dihexadecanoylphosphatidyl)inositol-5-phosphate, diammonium salt
Molecular Formula	C₄₁H₇₈O₁₆P₂ · 2NH₄
Formula Weight	925.1
Formulation	A lyophilized powder
Purity	>98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCCCCCCCCCC(OC[C@H](COP(O[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@H]1O)([O-])=O)OC(CCCCCCCCCCCCCCC)=O)=O.[2NH4]

Background Reading

Lapetina, E.G., Billah, M.M., and Cuatrecasas, P. The phosphatidylinositol cycle and the regulation of arachidonic acid production. Nature 292 367-369 (1981).

Pike, L.J., and Casey, L. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains. J Biol Chem 271 26453-26456 (1996).

Berridge, M.J. Inositol trisphosphate and calcium signalling. Nature 361 315-325 (1993).

Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

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PtdIns-(5)-P1 (1,2-dipalmitoyl) (ammonium salt) is available in the following screening library:

Bio-active Lipid II Screening Library (96-Well)

Size	Price	Quantity	Subtotal
100 µg	$58.00		$0.00
500 µg	$261.00		$0.00
1 mg	$464.00		$0.00
5 mg	$2,030.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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PtdIns-(5)-P1 (1,2-dipalmitoyl) (ammonium salt)

PtdIns-(5)-P1 (1,2-dipalmitoyl) (ammonium salt)

Description

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PtdIns-(5)-P₁ (1,2-dipalmitoyl) (ammonium salt)