1 Crismon, M.L. Pharmacokinetics and drug interactions of cholinesterase inhibitors administered in Alzheimer’s disease. Pharmacotherapy 18 47-54 (1998).

2 Drukarch, B., Leysen, J.E., and Stoof, J.C. Further analysis of the neuropharmacological profile of 9-amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer’s disease. Life Sci 42 1011-1017 (1988).

3 Giacobini, E. Cholinesterase inhibitors for Alzheimer’s disease therapy: From tacrine to future applications. Neurochem Int 32 413-419 (1998).

4 McKenna, M.T., Proctor, G.R., Young, L.C., et al. Novel tacrine analogues for potential use against Alzheimer’s disease: Potent and selective acetylcholinesterase inhibitors and 5-HT uptake inhibitors. J Med Chem 40 3516-3523 (1997).

5 Dolezal, V., Lisá, V., and Tucek, S. Effect of tacrine on intracellular calcium in cholinergic SN56 neuronal cells. Brain Res 769 219-224 (1997).

Drukarch, B., Leysen, J.E., and Stoof, J.C. Further analysis of the neuropharmacological profile of 9-amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer’s disease. Life Sci 42 1011-1017 (1988).

Giacobini, E. Cholinesterase inhibitors for Alzheimer’s disease therapy: From tacrine to future applications. Neurochem Int 32 413-419 (1998).

McKenna, M.T., Proctor, G.R., Young, L.C., et al. Novel tacrine analogues for potential use against Alzheimer’s disease: Potent and selective acetylcholinesterase inhibitors and 5-HT uptake inhibitors. J Med Chem 40 3516-3523 (1997).

Crismon, M.L. Pharmacokinetics and drug interactions of cholinesterase inhibitors administered in Alzheimer’s disease. Pharmacotherapy 18 47-54 (1998).

Dolezal, V., Lisá, V., and Tucek, S. Effect of tacrine on intracellular calcium in cholinergic SN56 neuronal cells. Brain Res 769 219-224 (1997).

Tacrine (hydrochloride) is available in the following screening library:

• Bio-active Lipid I Screening Library (96-Well)