Indomethacin morpholinamide (IMMA) is a selective CB2 receptor agonist. The binding constant for the CB2 receptor is 435 nM compared to >20,000 nM for the cannabinoid receptor, CB1.1
1
Gallant, M., Dufresne, C., Gareau, Y., et al. New class of potent ligands for the human peripheral cannabinoid receptor. Bioorg Med Chem Lett62263-2268(1996).
Gallant, M., Dufresne, C., Gareau, Y., et al. New class of potent ligands for the human peripheral cannabinoid receptor. Bioorg Med Chem Lett62263-2268(1996).
IMMA is available in the following screening
library: