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GuaiacolCayman Chemical Item Number 70430 (CAS 90-05-1) 
Guaiacol (CAS 90-05-1)
Description
Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of cyclooxygenase (COX) enzymes. It therefore serve as a reducing co-
1 Markey, C.M., Alward, A., Weller, P.E., et al. Quantitative studies of hydroperoxide reduction by prostaglandin H synthase. Reducing substrate specificity and the relationship of peroxidase to cyclooxygenase activities. J Biol Chem 262 6266-6279 (1987). 2 Doerge, D.R., Divi, R.L., and Churchwell, M.I. Identification of the colored guaiacol oxidation product produced by peroxidases. Anal Biochem 250 10-17 (1997). 3 Kulmacz, R.J., and Lands, W.E.M. Quantitative similarities in the several actions of cyanide on prostaglandin H synthase. Prostaglandins 29 175-190 (1985).
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Marquez, L.A., and Dunford, H.B. Mechanism of the oxidation of 3,5,3',5'-
Background ReadingMarkey, C.M., Alward, A., Weller, P.E., et al. Quantitative studies of hydroperoxide reduction by prostaglandin H synthase. Reducing substrate specificity and the relationship of peroxidase to cyclooxygenase activities. J Biol Chem 262 6266-6279 (1987). Doerge, D.R., Divi, R.L., and Churchwell, M.I. Identification of the colored guaiacol oxidation product produced by peroxidases. Anal Biochem 250 10-17 (1997). Marquez, L.A., and Dunford, H.B. Mechanism of the oxidation of 3,5,3',5'- Kulmacz, R.J., and Lands, W.E.M. Quantitative similarities in the several actions of cyanide on prostaglandin H synthase. Prostaglandins 29 175-190 (1985). Show all 4 Hide all but first 3 |
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