Cayman Chemical | NS-398 | Description (CAS 123653-11-2)

70590 NS-398

(CAS 123653-11-2)

Click image to enlarge

• See below for pricing and ordering

• See analysis tools

• See more Cyclooxygenase; Inhibitors; Neuroscience

Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC₅₀ values for human recombinant COX-1 and -2 are 75 and 1.77 µM, respectively.¹ The IC₅₀ values for ovine COX-1 and -2 are 220 and 0.15 µM, respectively.²

1 Barnett, J., Chow, J., Ives, D., et al. Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system. Biochim Biophys Acta 1209 130-139 (1994).

2 Johnson, J.L., Wimsatt, J., Buckel, S.D., et al. Purification and characterization of prostaglandin H synthase-2 from sheep placental cotyledons. Arch Biochem Biophys 324 26-34 (1995).

	Download Product Insert 125 Kb PDF
	Download Material Safety Data Sheet (MSDS) 18 Kb PDF
	Printer-friendly version of this page small PDF (usually less than 100 Kb)
	• US Letter paper 8½″ × 11″
	• A4 paper 21cm × 29.7cm

Purchase 70590 NS-398

Pricing is for North America only. Other customers should contact a distributor in their region.

This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

Pricing updated 2010-03-18.
Prices are subject to change without notice.

Related Products

Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.