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70604 3,4-Dihydroxyphenyl ethanol
Ba2774; 3-Hydroxytyrosol
(CAS 10597-60-1)
3,4-Dihydroxyphenyl ethanol Workbook Links
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3,4-Dihydroxyphenyl ethanol is a phenolic component of olive oil that inhibits both 12- and 5-LO. The IC50 values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13 µM, respectively. It does not inhibit, and may actually enhance, COX activity.1 3,4-Dihydroxyphenyl ethanol also protects LDL from both biological and chemical oxidation, suggesting a potential mechanism for the protective effects of olive oil against atherosclerosis.2
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1
Kohyama, N., Nagata, T., Fujimoto, S., et al. Inhibition of arachidonate lipoxygenase activities by 2-(3,4-dihydroxyphenyl)ethanol, a phenolic compound from olives. Biosci Biotech Biochem 61 347-350 (1997).
2
Grignaffini, P., Roma, P., Galli, C., et al. Protection of low-density lipoprotein from oxidation by 3,4-dihydroxyphenylethanol. Lancet 343 1296-1297 (1994).
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Pricing updated 2010-03-15.
Prices are subject to change without notice.
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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.
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