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3,4-Dihydroxyphenyl ethanol

Cayman Chemical Item Number 70604

Ba2774; 3-Hydroxytyrosol (CAS 10597-60-1)

3,4-Dihydroxyphenyl ethanol (CAS 10597-60-1)

See more	Lipoxygenase (84)

Description

3,4-Dihydroxyphenyl ethanol is a phenolic component of olive oil that inhibits both 12- and 5-LO. The IC₅₀ values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13 µM, respectively. It does not inhibit, and may actually enhance, COX activity.¹ 3,4-Dihydroxyphenyl ethanol also protects LDL from both biological and chemical oxidation, suggesting a potential mechanism for the protective effects of olive oil against atherosclerosis.²

1 Kohyama, N., Nagata, T., Fujimoto, S., et al. Inhibition of arachidonate lipoxygenase activities by 2-(3,4-dihydroxyphenyl)ethanol, a phenolic compound from olives. Biosci Biotechnol Biochem 61 347-350 (1997).

2 Grignaffini, P., Roma, P., Galli, C., et al. Protection of low-density lipoprotein from oxidation by 3,4-dihydroxyphenylethanol. Lancet 343 1296-1297 (1994).

Synonyms	Ba2774 3-Hydroxytyrosol
Formal Name	4-(2-hydroxyethyl)-1,2-benzenediol
CAS Number	10597-60-1
Molecular Formula	C₈H₁₀O₃
Formula Weight	154.2
Formulation	A solution in ethanol
Purity	≥98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard OCCc1ccc(O)c(O)c1

Background Reading

Kohyama, N., Nagata, T., Fujimoto, S., et al. Inhibition of arachidonate lipoxygenase activities by 2-(3,4-dihydroxyphenyl)ethanol, a phenolic compound from olives. Biosci Biotechnol Biochem 61 347-350 (1997).

Size	Price	Quantity	Subtotal
5 mg	$12.00		$0.00
10 mg	$23.00		$0.00
50 mg	$96.00		$0.00
100 mg	$168.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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