Cayman Chemical | Methyl α-Linolenyl Fluorophosphonate

70662 Methyl α-Linolenyl Fluorophosphonate

MLnFP

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Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Methyl α-linolenyl fluorophosphonate (MLnFP) is an analog of methyl arachidonyl fluorophosphonate (MAFP; Catalog No. 70660), which has been widely studied as an inhibitor of phospholipases, FAAH, and as a CB receptor ligand.^1,2,3 The pharmacology of the α-linolenyl analog of MAFP has not been completely investigated.

1 Huang, Z., Liu, S., Street, I., et al. Methyl arachidonyl fluorophosphonate, a potent irreversible cPLA₂ inhibitor, blocks the mobilization of arachidonic acid in human platelets and neutrophils. Mediators Inflamm 3 307-308 (1994).

2 Deutsch, D.G., Omeir, R., Arreaza, G., et al. Methyl arachidonyl fluorophosphonate: A potent irreversible inhibitor of anandamide amidase. Biochem Pharmacol 53 255-260 (1997).

3 Lio, Y., Reynolds, L.J., Balsinde, J., et al. Irreversible inhibition of Ca2+-independent phospholipase A₂ by methyl arachidonyl fluorophosphonate. Biochim Biophys Acta 1302 55-60 (1996).

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Warning This product is not for human or veterinary use.

Pricing updated 2010-03-19.
Prices are subject to change without notice.

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