Cayman Chemical | Methyl γ-Linolenyl Fluorophosphonate

70664 Methyl γ-Linolenyl Fluorophosphonate

MγLnFP

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MγLnFP is an analog of methyl arachidonyl fluozophosphonate (MAFP; Catalog No. 70660), which has been widely studied as an inhibitor of phospholipases, FAAH, and as a CB receptor ligand.^1,2,3 The pharmacology of the γ-linolenyl analog of MAFP has not been completely investigated.

1 Huang, Z., Liu, S., Street, I., et al. Methyl arachidonyl fluorophosphonate, a potent irreversible cPLA₂ inhibitor, blocks the mobilization of arachidonic acid in human platelets and neutrophils. Mediators Inflamm 3 307-308 (1994).

2 Deutsch, D.G., Omeir, R., Arreaza, G., et al. Methyl arachidonyl fluorophosphonate: A potent irreversible inhibitor of anandamide amidase. Biochem Pharmacol 53 255-260 (1997).

3 Lio, Y., Reynolds, L.J., Balsinde, J., et al. Irreversible inhibition of Ca2+-independent phospholipase A₂ by methyl arachidonyl fluorophosphonate. Biochim Biophys Acta 1302 55-60 (1996).

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Pricing updated 2010-03-18.
Prices are subject to change without notice.

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