Ketorolac is a non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 31.5 µM and 60.5 µM, respectively.1
1
Laneuville, O., Breuer, D.K., DeWitt, D.L., et al. Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther271927-934(1994).
Synonyms
Toradol
Formal Name
(±)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, tris(hydroxymethyl)aminomethane salt
CAS Number
74103-07-4
Molecular Formula
C15H12NO3 · C4H12NO3
Formula Weight
376.4
Formulation
A crystalline solid
Purity
>99%
λmax
243, 317 nm
Stability
2 years
Storage
Room temperature
Shipping
Room temperature
in continental US; may vary elsewhere
Laneuville, O., Breuer, D.K., DeWitt, D.L., et al. Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther271927-934(1994).
Ketorolac (tromethamine salt) is available in the following screening
library: