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Caffeic Acid phenylethyl ester

Cayman Chemical Item Number 70750

2-Phenylethyl Caffeate; CAPE; β-Phenylethyl Caffeate (CAS 104594-70-9)

Caffeic Acid phenylethyl ester (CAS 104594-70-9)

See more	Nuclear Receptors (86)

Description

Caffeic acid phenylethyl ester is an active component of propolis from honeybee hives. It is known to have antimitogenic, anticarcinogenic, anti-inflammatory, and immunomodulatory properties. It is a potent and specific inhibitor of nuclear transcription factor, NF-κB, activation.¹

1 Natarajan, K., Singh, S., Burke, T.R., et al. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB. Proc Natl Acad Sci USA 93 9090-9095 (1996).

Synonyms	2-Phenylethyl Caffeate CAPE β-Phenylethyl Caffeate
Formal Name	(E)-3-(3,4-dihydroxyphenyl)-2-propenoic acid, 2-phenylethyl ester
CAS Number	104594-70-9
Molecular Formula	C₁₇H₁₆O₄
Formula Weight	284.3
Formulation	A crystalline solid
Purity	>98%
λ_max	246, 300, 331 nm
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard O=C(OCCc1ccccc1)\C=C/c1ccc(O)c(O)c1

Background Reading

Natarajan, K., Singh, S., Burke, T.R., et al. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB. Proc Natl Acad Sci USA 93 9090-9095 (1996).

Burke, T.R., Fesen, M.R., Mazumder, A., et al. Hydroxylated aromatic inhibitors of HIV-1 integrase. J Med Chem 38 4171-4178 (1995).

Caffeic Acid phenylethyl ester is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
50 mg	$55.00		$0.00
100 mg	$105.00		$0.00
500 mg	$440.00		$0.00
1 g	$770.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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