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LY294002

Cayman Chemical Item Number 70920

(CAS 154447-36-6)

LY294002 (CAS 154447-36-6)

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Description

LY294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor with a 2.7-fold greater potency than quercetin. LY294002 inhibits purified PI3K with an IC50 of 1.4 µM.1

1 Vlahos, C.J., Matter, W.F., Hui, K.Y., et al. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269 5241-5248 (1994).

Formal Name 2-​(4-​morpholinyl)-​8-​phenyl-​4H-​1-​benzopyran-​4-​one
CAS Number 154447-36-6
Molecular Formula C19H17NO3
Formula Weight 307.3
Formulation A crystalline solid
Purity >98%
λmax 223, 302 nm
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O=c1cc(oc2c(cccc12)​c1ccccc1)​N1CCOCC1

Background Reading

Vlahos, C.J., Matter, W.F., Hui, K.Y., et al. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269 5241-5248 (1994).

LY294002 is available in the following screening libraries:

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