70940  (+)-Catechin (hydrate)

D-(+)-Catechin (hydrate); Cyanidol (hydrate); Catechuic Acid (hydrate) (CAS 88191-48-4)

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• See more Antioxidants; Flavonoids; Oxidative Injury

Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Catechin is a polyphenolic flavonoid which has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechin is a more potent antioxidant than ascorbate or α-tocopherol in certain in vitro assays of lipid peroxidation.1 Catechin inhibits the free radical-induced oxidation of isolated LDL by AAPH.2 It has also been reported to act as an inhibitor of COX-1 with an IC50 of about 80 µM.3 Catechin and other related procyanidin compounds have antitumor activity when tested in a two-stage mouse epidermal carcinoma model employing topical application.1
1  Zhao, J., Wang, J., Chen, Y., et al. Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent. Carcinogenesis 20 1737-1745 (1999).
2  Frémont, L., Belguendouz, L., Delpal, S. Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids. Life Sci 64 2511-2521 (1999).
3  Noreen, Y., Serrano, G., Perera, P. Flavan-3-ols isolated from some medicinal plants inhibiting COX-1 and COX-2 catalyzed prostaglandin biosynthesis. Planta Med 64 520-524 (1998).


Purchase 70940 (+)-Catechin (hydrate)

Pricing is for North America only. Other customers should contact a distributor in their region.

This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

Pricing updated 2010-03-18.
Prices are subject to change without notice.

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