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Oleoyl OxazolopyridineCayman Chemical Item Number 71650 CAY10400 (CAS 288862-58-8) 
Oleoyl Oxazolopyridine (CAS 288862-58-8)
Description
Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. Oleoyl oxazolopyridine is a potent inhibitor of FAAH exhibiting Ki values of 1.3 and 2.3 nM for the human and rat enzymes, respectively.1 Oleoyl oxazolopyridine is approximately 35-
1 Boger, D.L., Sato, H., Lerner, A.E., et al. Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide. Proc Natl Acad Sci USA 97 5044-5049 (2000).
Background ReadingBoger, D.L., Sato, H., Lerner, A.E., et al. Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide. Proc Natl Acad Sci USA 97 5044-5049 (2000). Oleoyl Oxazolopyridine is available in the following screening library: |
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