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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

CAY10401

Cayman Chemical Item Number 71652

(CAS 288862-89-5)

CAY10401 (CAS 288862-89-5)

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Description

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10401 is a selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.14 nM.1 CAY10401 is approximately 580 fold more potent than oleyl trifluoromethyl ketone when assayed under the same conditions.1

1 Boger, D.L., Sato, H., Lerner, A.E., et al. Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide. Proc Natl Acad Sci USA 97 5044-5049 (2000).

Formal Name 1-​oxazolo[4,​5-​b]pyridin-​2-​yl-​9-​octadecyn-​1-​one
CAS Number 288862-89-5
Molecular Formula C24H34N2O2
Formula Weight 382.5
Formulation A solution in methyl acetate
Purity >98%
λmax 234, 297 nm
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCCCC(=O)​c1nc2ncccc2o1

Background Reading

Boger, D.L., Sato, H., Lerner, A.E., et al. Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide. Proc Natl Acad Sci USA 97 5044-5049 (2000).

CAY10401 is available in the following screening library:

Size Price Quantity Subtotal
100 µg $28.00 $0.00
500 µg $126.00 $0.00
1 mg $224.00 $0.00
5 mg $980.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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