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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Colorimetric COX (ovine) Inhibitor Screening Assay Kit

Cayman Chemical Item Number 760111

Colorimetric COX (ovine) Inhibitor Screening Assay Kit

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Colorimetric COX (ovine) Inhibitor Screening Assay Kit Analysis Tools

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Description

The Colorimetric COX Inhibitor Screening Assay measures the peroxidase component of cyclooxygenases. The peroxidase activity is assayed colorimetrically by monitoring the appearance of oxidized N,N,N',N'-tetramethyl-p-phenylenediamine (TMPD) at 590 nm.1 Inhibition of COX activity, measured by TMPD oxidation, by a variety of selective and nonselective inhibitors, shows changed potencies similar to those observed with other in vitro methods. The Colorimetric COX Inhibitor Screening assay includes both ovine COX-1 and COX-2 enzymes in order to screen isozyme-specific inhibitors. The Cayman Colorimetric COX Assay is a time saving tool for screening vast numbers of inhibitors.

1 Kulmacz, R.J., and Lands, W.E.M. Requirements for hydroperoxide by the cyclooxygenase and peroxidase activities of prostaglandin H synthase. Prostaglandins 25 531-540 (1983).

Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere

Background Reading

Kulmacz, R.J., and Lands, W.E.M. Requirements for hydroperoxide by the cyclooxygenase and peroxidase activities of prostaglandin H synthase. Prostaglandins 25 531-540 (1983).

760111-96WELL
96-Well Solid Plate (Colorimetric Assay)
Colorimetric COX Assay COX-1 (ovine) 1 ea
Colorimetric COX Assay COX-2 (ovine) 1 ea
Colorimetric COX Assay Arachidonic Acid (substrate) 1 ea
Colorimetric COX Assay Buffer (10X) 1 ea
Colorimetric COX Assay Potassium Hydroxide 1 ea
Colorimetric COX Assay Heme 1 ea
Colorimetric COX Assay Colorimetric Substrate 1 ea
Size Price Quantity Subtotal
96 wells $371.00 $0.00
Bulk Contact
Cart Total $0.00

This product is also available to buy in bulk quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

You may be eligible to receive a free sample Colorimetric COX (ovine) Inhibitor Screening Assay Kit under the Cayman Challenge program.

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