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Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

P-Glycoprotein Drug Interaction Assay Kit

Cayman Chemical Item Number 789201

P-gp Drug Interaction Assay Kit

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Description

P-Glycoprotein (P-gp) is an active plasma membrane transporter involved in drug pharmacokinetics and cellular detoxification. P-gp exhibits a high drug-dependent ATP hydrolysis activity that is a reflection of its drug transport ability. The test of drug stimulation or inhibition of ATPase activity may be used to screen the potential drug interaction with P-gp. This assay provides an in vitro screening method for testing drug interaction with P-gp based on the study of modulation of basal or induced ATPase activity from enriched P-gp membrane vesicle preparations. P-gp ATPase activity is measured by a spectrophotometric method based on continuous monitoring of ADP formation in the vesicle suspension medium in a 96 well plate format. Data are analyzed by comparing the variation of the basal or stimulated activities to reference activities.
Synonyms
  • P-gp Drug Interaction Assay Kit
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Size Global Purchasing
96 wells See a distributor in your region for pricing

This product is also available to buy in bulk quantities.

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Warning This product is not for human or veterinary use.

Let Cayman analyze your samples for you. See EIA Service for details and availability.

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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

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