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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Thioarginine (hydrobromide)

Cayman Chemical Item Number 80240

Thioarginine (hydrobromide)

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Description

L-Arginine serves as a common substrate for both nitric oxide synthase (NOS) and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with Nω-hydroxy-L-arginine (NOHA) formed as an intermediate. Arginase, on the other hand, catalyzes the hydrolysis of arginine into urea and L-ornithine. Thioarginine (hydrobromide) is a colorimetric substrate for arginase that provides the basis for continuous spectrophotometric measurement of enzyme activity.1 It exhibits Km and kcat values of 0.5 mM and 18,000 min−1, respectively, which are similar to physiological substrate arginine.1 The thiol product of the reaction reacts with DTNB to produce 2-nitro-5-thiobenzoate for easy visualization at 405-420 nm.

1 Han, S.H., and Viola, R.E. A spectrophotometric assay of arginase. Anal Biochem 295 117-119 (2001).

Formal Name 5-​[(aminoiminomethyl)thio]-​L-​norvaline
Molecular Formula C6H13N3O2S · HBr
Formula Weight 272.2
Formulation A crystalline solid
Purity >95%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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N/C(SCCC[C@H]​(N)​C(O)​=O)​=N/[H]​.Br

Background Reading

Han, S.H., and Viola, R.E. A spectrophotometric assay of arginase. Anal Biochem 295 117-119 (2001).

Thioarginine (hydrobromide) is available in the following screening library:

Size Price Quantity Subtotal
1 mg $46.00 $0.00
5 mg $207.00 $0.00
10 mg $368.00 $0.00
50 mg $1,610.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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