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N^ω-propyl-L-Arginine

Cayman Chemical Item Number 80587

(CAS 137361-05-8)

Nω-propyl-L-Arginine (CAS 137361-05-8)

See more	Neuroscience (654) Nitric Oxide (101)

Description

N^ω-Propyl-L-Arginine is a potent and selective inhibitor of neuronal nitric oxide synthase (nNOS). N^ω-Propyl-L-Arginine is a competitive inhibitor of bovine nNOS having a K_i value of 57 nM.¹ The K_i values for eNOS (bovine) and iNOS (murine) are 8.5 and 180 µM, respectively. N^ω-propyl-L-Arginine therefore exhibits 3,000-fold and 150-fold selectivity for the neuronal isoform versus the inducible (murine) and endothelial (bovine) isoforms of NOS, respectively.¹

1 Zhang, H.Q., Fast, W., Marletta, M.A., et al. Potent and selective inhibition of neuronal nitric oxide synthase by N^ω-propyl-L-arginine. J Med Chem 40 3869-3870 (1997).

Formal Name	N5-[imino(propylamino)methyl]-L-ornithine
CAS Number	137361-05-8
Molecular Formula	C₉H₂₀N₄O₂
Formula Weight	216.3
Formulation	A crystalline solid
Purity	>98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCNC(=N)NCCC[C@H](N)C(=O)O

Background Reading

Zhang, H.Q., Fast, W., Marletta, M.A., et al. Potent and selective inhibition of neuronal nitric oxide synthase by N^ω-propyl-L-arginine. J Med Chem 40 3869-3870 (1997).

Size	Price	Quantity	Subtotal
5 mg	$43.00		$0.00
10 mg	$82.00		$0.00
50 mg	$344.00		$0.00
100 mg	$602.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Nω-propyl-L-Arginine