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AMT (hydrochloride)

Cayman Chemical Item Number 81010

(CAS 21463-31-0)

AMT (hydrochloride) (CAS 21463-31-0)

See more	Nitric Oxide (101)

Description

AMT is a potent, relatively selective inhibitor of iNOS with a K_i of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations; the IC₅₀ values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively.¹

1 Nakane, M., Klinghofer, V., Kuk, J.E., et al. Novel potent and selective inhibitors of inducible nitric oxide synthase. Mol Pharmacol 47 831-834 (1995).

Formal Name	5,6-dihydro-6-methyl-4H-1,3-thiazin-2-amine, hydrochloride
CAS Number	21463-31-0
Molecular Formula	C₅H₁₀N₂S · HCl
Formula Weight	166.7
Formulation	A crystalline solid
Purity	>98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CC1CCN=C(N)S1

Background Reading

Nakane, M., Klinghofer, V., Kuk, J.E., et al. Novel potent and selective inhibitors of inducible nitric oxide synthase. Mol Pharmacol 47 831-834 (1995).

Size	Price	Quantity	Subtotal
10 mg	$73.00		$0.00
50 mg	$329.00		$0.00
100 mg	$584.00		$0.00
500 mg	$2,555.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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