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2-Imino-4-methylpiperidine (acetate)

Cayman Chemical Item Number 81015

(CAS 165383-72-2)

2-Imino-4-methylpiperidine (acetate) (CAS 165383-72-2)

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Description

2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 µM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 µM.1

1 Webber, R.K., Metz, S., Moore, W.M., et al. Substituted 2-iminopiperidines as inhibitors of human nitric oxide synthase isoforms. J Med Chem 41 96-101 (1998).

Formal Name 3,​4,​5,​6-​tetrahydro-​4-​methyl-​2-​pyridinamine,​ acetate
CAS Number 165383-72-2
Molecular Formula C6H12N2 · C2H3O2
Formula Weight 171.2
Formulation A crystalline solid
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CC1CCN=C([NH3+]​)​C1.C[C-]​([O-]​)​=O

Background Reading

Webber, R.K., Metz, S., Moore, W.M., et al. Substituted 2-iminopiperidines as inhibitors of human nitric oxide synthase isoforms. J Med Chem 41 96-101 (1998).

2-Imino-4-methylpiperidine (acetate) is available in the following screening library:

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