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Curcumin

Cayman Chemical Item Number 81025

Turmeric Yellow; Indian Saffron (CAS 458-37-7)

Curcumin (CAS 458-37-7)

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Description

Curcumin is a natural product with antioxidant, anti-tumor, and anti-inflammatory properties. Curcumin inhibits the induction of NOS in macrophages.1,2,3

1 Conney, A.H., Lysz, T., Ferraro, T., et al. Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Adv Enzyme Regul 31 385-396 (1991).

2 Tanaka, T., Makita, H., Ohnishi, M., et al. Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: Comparison with the protective effect of β-carotene. Cancer Res 54 4653-4659 (1994).

3 Brouet, I., and Ohshima, H. Curcumin, an anti-tumor promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun 206 533-540 (1995).

Synonyms
  • Turmeric Yellow
  • Indian Saffron
Formal Name 1,​7-​bis(4-​hydroxy-​3-​methoxyphenyl)-​1E,​6E-​heptadiene-​3,​5-​dione
CAS Number 458-37-7
Molecular Formula C21H20O6
Formula Weight 368.4
Formulation A crystalline solid
Purity ≥90%
λmax 427 nm
Stability 2 years
Storage Room temperature
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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COc1cc(/C=C\C(=O)​CC(=O)​\C=C/c2ccc(O)​c(OC)​c2)​ccc1O

Background Reading

Tanaka, T., Makita, H., Ohnishi, M., et al. Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: Comparison with the protective effect of β-carotene. Cancer Res 54 4653-4659 (1994).

Brouet, I., and Ohshima, H. Curcumin, an anti-tumor promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun 206 533-540 (1995).

Conney, A.H., Lysz, T., Ferraro, T., et al. Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Adv Enzyme Regul 31 385-396 (1991).

Curcumin is available in the following screening library:

Size Global Purchasing
1 g See a distributor in your region for pricing
5 g See a distributor in your region for pricing
10 g See a distributor in your region for pricing
50 g See a distributor in your region for pricing

This product is available in custom sizes and/or larger quantities.

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Warning This product is not for human or veterinary use.

Related Products

Bisdemethoxycurcumin
Celastrol
Curcumin (technical grade)
Demethoxycurcumin
Dimethoxycurcumin
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