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Curcumin (technical grade)

Cayman Chemical Item Number 81025.1

Turmeric Yellow; Indian Saffron (CAS 458-37-7)

Curcumin (technical grade) (CAS 458-37-7)

See more	Antioxidants (63) Cancer (666) Nitric Oxide (101) Oxidative Injury (291)

Description

Curcumin is an extract of turmeric root with antioxidant, anti-tumor, and anti-inflammatory properties. Curcumin inhibits the induction of NOS in macrophages.^1,2,3

1 Conney, A.H., Lysz, T., Ferraro, T., et al. Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Adv Enzyme Regul 31 385-396 (1991).

2 Tanaka, T., Makita, H., Ohnishi, M., et al. Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: Comparison with the protective effect of β-carotene. Cancer Res 54 4653-4659 (1994).

3 Brouet, I., and Ohshima, H. Curcumin, an anti-tumor promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun 206 533-540 (1995).

Synonyms	Turmeric Yellow Indian Saffron
Formal Name	1,7-bis(4-hydroxy-3-methoxyphenyl)-1E,6E-heptadiene-3,5-dione
CAS Number	458-37-7
Molecular Formula	C₂₁H₂₀O₆
Formula Weight	368.4
Formulation	A crystalline solid
Purity	≥65%
λ_max	427 nm
Stability	2 years
Storage	Room temperature
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard O=C(CC(/C=C/C1=CC(OC)=C(O)C=C1)=O)/C=C/C2=CC(OC)=C(O)C=C2

Background Reading

Tanaka, T., Makita, H., Ohnishi, M., et al. Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: Comparison with the protective effect of β-carotene. Cancer Res 54 4653-4659 (1994).

Conney, A.H., Lysz, T., Ferraro, T., et al. Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Adv Enzyme Regul 31 385-396 (1991).

Brouet, I., and Ohshima, H. Curcumin, an anti-tumor promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun 206 533-540 (1995).

Size	Global Purchasing
5 g	See a distributor in your region for pricing
10 g	See a distributor in your region for pricing
50 g	See a distributor in your region for pricing
100 g	See a distributor in your region for pricing

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Curcumin

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