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Curcumin

Cayman Chemical Item Number 81025

Turmeric Yellow; Indian Saffron (CAS 458-37-7)

Curcumin (CAS 458-37-7)

See more	Antioxidants (62) Cancer (606) Nitric Oxide (101) Oxidative Injury (258)

Description

Curcumin is a natural product with antioxidant, anti-tumor, and anti-inflammatory properties. Curcumin inhibits the induction of NOS in macrophages.^1,2,3

1 Conney, A.H., Lysz, T., Ferraro, T., et al. Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Adv Enzyme Regul 31 385-396 (1991).

2 Tanaka, T., Makita, H., Ohnishi, M., et al. Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: Comparison with the protective effect of β-carotene. Cancer Res 54 4653-4659 (1994).

3 Brouet, I., and Ohshima, H. Curcumin, an anti-tumor promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun 206 533-540 (1995).

Synonyms	Turmeric Yellow Indian Saffron
Formal Name	1,7-bis(4-hydroxy-3-methoxyphenyl)-1E,6E-heptadiene-3,5-dione
CAS Number	458-37-7
Molecular Formula	C₂₁H₂₀O₆
Formula Weight	368.4
Formulation	A crystalline solid
Purity	≥90%
λ_max	427 nm
Stability	2 years
Storage	Room temperature
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard COc1cc(/C=C\C(=O)CC(=O)\C=C/c2ccc(O)c(OC)c2)ccc1O

Background Reading

Tanaka, T., Makita, H., Ohnishi, M., et al. Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: Comparison with the protective effect of β-carotene. Cancer Res 54 4653-4659 (1994).

Brouet, I., and Ohshima, H. Curcumin, an anti-tumor promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun 206 533-540 (1995).

Conney, A.H., Lysz, T., Ferraro, T., et al. Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Adv Enzyme Regul 31 385-396 (1991).

Curcumin is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
1 g	$12.00		$0.00
5 g	$54.00		$0.00
10 g	$96.00		$0.00
50 g	$420.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

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Dimethoxycurcumin

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