See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

S-isopropyl Isothiourea (hydrobromide)

Cayman Chemical Item Number 81290

S-isopropyl ITU; IPTU (CAS 4269-97-0)

S-isopropyl Isothiourea (hydrobromide) (CAS 4269-97-0)

See more

Description

S-Isopropylisothiourea (hydrobromide) (IPTU (hydrobromide) is a potent inhibitor of NOS in vitro but may lack good in vivo efficacy due to poor cellular penetration. The Ki values are 9.8, 22, and 37 nM using purified human iNOS, eNOS, and nNOS, respectively.1

1 Garvey, E.P., Oplinger, J.A., Tanoury, G.J., et al. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. J Biol Chem 269 26669-26676 (1994).

Synonyms
  • S-isopropyl ITU
  • IPTU
Formal Name isopropyl carbamimidothioate,​ hydrobromide
CAS Number 4269-97-0
Molecular Formula C4H10N2S · HBr
Formula Weight 199.1
Formulation A crystalline solid
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
N/C(SC(C)​C)​=N/[H]​.Br

Background Reading

Garvey, E.P., Oplinger, J.A., Tanoury, G.J., et al. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. J Biol Chem 269 26669-26676 (1994).

S-isopropyl Isothiourea (hydrobromide) is available in the following screening library:

Size Price Quantity Subtotal
50 mg $27.00 $0.00
100 mg $51.00 $0.00
500 mg $216.00 $0.00
1 g $378.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

NG-amino-L-Arginine (hydrochloride)
S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea (hydrochloride)
α-Guanidinoglutaric Acid

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?